Adriano studied Animal Science at Cornell University and started working in the Cornell University College of Veterinary Medicine department of Clinical Sciences, in collaboration with the Baker Institute for Animal Health. He spent several years engaged in practical and analytical research work on canine hip dysplasia before accepting a position in the Biotechnology Resource Center. After a year working on DNA sequencing, Adriano transitioned to the Bioinformatics Facility as the primary developer of the Laboratory Information Management System, which was built from the ground up and is used by each facility today.