Biotechnology Resource CenterProteomics Facility
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Services include gel-based protein ID (1D gel and 2D gel) and solution-based shotgun protein ID. Click here for more information.
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Services include detection and quantitation of post-translational modifications (PTMs), including phosphorylation, deamidation, N-glycosylation, ubiquitination, amino acid mutations, acylation and N-/C-terminal sequence determination. Click here for more information.
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Services include isobaric tag relative absolute protein quantitation (iTRAQ)/Tandem Mass Tag (TMT), stable isotope labeling with amino acids in cell culture (SILAC), dimethyl labeling, and label-free detection (e.g., XIC, spectral counting, and SRM). Click here for more information.
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Services can be used for profiling small molecules in complex mixtures, using liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis, and for small molecule quantitation, using selected reaction monitoring (SRM). Click here for more information.
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Services include sample separation, enrichment/depletion, digestion, desalting, concentration, and quality assessment/quality control. Click here for more information.
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A wide range of software tools for proteomics and mass spectrometry data analysis are available through the core. Click here for more information.
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Consultation on project design and data analysis is available upon request. Coordinated consultation support is available with all the other BRC cores. Software tools for data analysis are available through the core. Click here for more information.
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Training is available for the open-access instruments in the core and on the use of software analysis tools. The core also organizes and hosts proteomics and mass spectrometry seminars, educational workshops, and the Cornell Proteomics Program. Click here for more information.