Skip to main content

Cornell University

Intact protein analysis

This analysis measures the molecular weight of intact protein under native or denatured conditions.

Protein samples should be in solution, and can be analyzed by either of the following ways:

  • by online LC-MS (for desalting and relatively complex)
  • by infusion or loop injection for purified proteins without need of desalting
  • by infusion or loop injection for most protein-ligand or protein-protein non-covalent interactions under native conditions

To order an intact protein analysis, click on the service link below.