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Post-translational modifications (PTM)

Our full service includes sample preparation, sample analysis and data interpretation. If you want to do the sample preparation or data interpretation yourself, let us know during the project consultation.

The service fees are broken down in the tables below.

Service pricing

Sample preparation
DescriptionInternal price (Cornell and Cornell affiliates)External price
Bradford Assay (set up) $40 $64
Bradford Assay (per sample) $5 $8
Affinity depletion of serum high abundant proteins (per sample) $120 $192
TMT 10-plex reagent (per set of samples) $750 $1,200
TMT 10-plex labeling and sample preparation (per set of samples) $800 $1,280
TMT 11-plex reagent (per set of samples) $880 $1,408
TMT 11-plex labeling and sample preparation (per set of samples) $880 $1,408
TMT 16-plex reagent (per set of samples) $1,500 $2,400
TMT 16-plex labeling and sample preparation (per set of samples) $1,300 $2,080
Gel-based protein quantitation for shotgun (per set of samples) $200 $320
dimethylation duplex labeling (per set of samples) $350 $560
dimethylation triplex labeling (per set of samples) $450 $720
mini SDS-PAGE (precast) (per gel) $85 $136
Gel imaging (per hour) $60 $96
In-gel Digest/Extraction, manual (set up) $100 $160
In-gel Digest/Extraction, manual (per sample) $50 $80
In-solution digestion (set up) $100 $160
In-solution digestion (per sample) $50 $80
Strap supplier for insolution digestion (per sample) $10 $16
SPE Cleanup, manual (per sample) $25 $40
Beads-based IMAC or TiO2 enrichment (per sample) $60 $96
MCX/MAX Cartridge (manual) (per sample) $60 $96
Other beads-based affinity enrichment (per sample) $60 $96
HRP manual fractionation (per sample) $100 $160
HPLC/MS
DescriptionInternal price (Cornell and Cornell affiliates)External price
Ion exchange chromatography with fractions collection (per sample) $250 $400
high pH reverse phase with fractions collection (per sample) $250 $400
HILIC chromtography with fractions collection (per sample) $250 $400
nanoLC-MS/MS: 90-120min gradient in Orbitrap Fusion/Eclipse (per sample) $250 $400
nanoLC-MS/MS: 90-120min gradient in Orbitrap Eclipse RTS (per sample) $300 $480
LC/MS/MS for protein PTMs in two runs (CID/HCD/ETD) (per sample) $400 $640
Hypothesis-driven LC-MS/MS run for PTM discovery in QTrap (per sample) $160 $256
HPLC/MS data interpretation
DescriptionInternal price (Cornell and Cornell affiliates)External price
Peptide quantitation by extracted ion chromatogram (per hour) $100 $160
MS/MS manual data interpretation and inspection (per hour for all relevant spectra) $100 $160
Quantitation analysis for label-free nanoLC-MS/MS (per set of quan) $250 $400
Customized database interrogation (per database) $75 $120
LC/MS spectra slides for presentation (per figure) $200 $320
Additional database search and report (per hour) $100 $160